I just checked mine and the slide DOES catch slightly on the inside top of the hammer when you cycle the slide slowly. Can't notice it normally. But I doubt that has anything to do with FTF/FTE problems if you have them. I shoot Remington subsonic almost exclusively when I shoot with my suppressors, which is a lot of the time; nary a hiccup of any sort. Same results without the cans.
Otherwise, it can be very picky about ammo. I've found Remington to be one of the most reliable brand in my P22. Also, try to use jacketed rounds, that can help decrease the malfunctions also.