I've hunted with a 44 Mag for at least 30 years, I've taken Elk, Deer, Antelope, Javalina, Mountain Lion, Black Bear, Coyotes, Rabbits and Squirrles with it. It's a good hunting round as long as you stay within it's limits.
A year ago I had a chance to spend time shooting with a couple of guys from S&W and Ruger. I got to shoot the Ruger 454 Alaskan and their 480, I also got the shoot the 460 S&W and the 500 S&W. I got to shoot at least 50 rounds per gun.
When you shoot the 45 Colt in the 460 you barely notice the recoil and the 454 is about the same. When I can afford it the S&W 460 is my next gun. It was accurate, confortable to shoot and head and shoulders over the rest of the rounds I got to shoot. It's a great gun.