Yes, they do make locking cases.
What are your circumstances at home/ A child? Just U?
I have a child on the way now, so I am training myself to not leave guns out anymore, but they are still all loaded. And, in the past, I've just kept all my guns loaded. If U have no kids - get a locking case or a small pistol safe, and leave it at that.
If U have a child, maybe get a strigger lock that will work on a semi auto. They do make some cable locks U can use too (most new guns come w/ them, but U can buy them as well - or get them free from your local Sheriff's Office usually).