.357 Sig is coming, but not available yet. Only 9mm and .40 are available, as are the kits to change from one to the other. .45, I believe is next, then .357. Compact is available. Sub compact is on the way. I believe Full size is available (or is at least on their site). P250 is a very accurate pistol. Try it if you can. There is a good thread on Sigforum on the P250 and of course I have a site dedicated to the P250 (P250sig.com). Between these 3 sites, I'm sure you will have enough info to help with your decision. I love mine, obviously. Good luck.