I'd only suggest going with the P229 in 9mm for the expense of the ammo for practice. If you plan on carrying as a BACKUP for hunting, either will do. If you plan on pistol hunting, anything in the big-game size range, I'd opt for a 44Mag revolver.
Both the 229 and 220 are excellent guns. Pricey, but worth the money for most of their owners. The 45ACP will run you almost twice as much money as the 9mm ammo to shoot currently.
Both, with modern JHP ammo, are fine vs 2-legged predators...