There is only one difference between the old,full size,Vaquero and the Blackhawk is the sights..Blackhawk has them and the Vaquero doesn't,adjustable sights I mean..
I am not sure but I believe the new smaller Vaquero will not handle the heavy loadings of the larger gun..
As far as a hunting caliber goes there isn't much or anything in North America that hasn't fallen to the 45colt including the two legged varmits..And this was done with either black powder or smokeless at factory velocity's..
The cartridge has worked for about 135 years,there must be something going for it..


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