The Blackhawk has adjustable sights and the Vaquero has fixed sights.
The only Beretta I own is a semi-automatic pistol and I don't own any Uberti's.
Personally, I would stick with Rugers and here's why. Not too long ago the end of the base pin on my Single Six broke. I called Ruger prepared to give them the date it was purchased, where, the serial number, etc. When I explained what happened, all they wanted to know was my name and address so they would know where to send the replacement!
Before that happened, I was looking for a .357 Magnum and looked at the Beretta Stampede, Uberti Cattelman and other brands in that price range, but based on that experience with my Single Six, I bought a Blackhawk. End of story!