Just a little update...
Looks like I will be going for the Sig P220 Carry despite the low capacity compared to some others. I really prefer to have a .45ACP at my disposal, and the P220 Carry seems just about perfect for me. I've done a lot of research, and even listened to people present the "shot placement" case as it pertains to 9mm. FWIW, 9mm is a great round if you are at 100% capacity and are able to but rounds exactly where you want them. However, I know that I can put someone down more reliably with .45 even with less than ideal shot placement, so that wins for me. Not to mention, if I have to draw on someone, there's something about looking down the barrel o f a larger caliber handgun that makes some people think twice.
As an aside, I'll be going with a Glock 21 for a "nightstand gun". If I'm woken up from a deep sleep to find that I need to grab my weapon, I need a simple "point-and-click" system that will fire reliably.
Thanks again for all your suggestions. There are lot of guns listed that will end up in my "inventory" at some point.