Depending on what you are hunting, I can tell you from personal experience that Winchester 175gr. SilverTips will do a number on a whitetail and mule deer as long as you keep your ranges reasonable. Shot placement is CRITICAL. I have taken two whitetail and one mule deer, longest shot was 35 yards. I have been told that the COR-BON 180gr. HP works well, but I have not tried it yet.
Although hunting with a 10mm may be completely legal in your state, I personally am dead set against it.
Bear in mind that I live in a place where deer are a plague, and tame enough that one can take one by mere manual strangulation. Nevertheless, this county mandates either a shotgun or a bow. Period.
Why is that?
Because you still have a duty to the deer, to kill it humanely, quickly, and surely, preferably with one shot.
The odds of doing that with a pistol of self-defense caliber are much, much worse than the odds of doing it with just about any hunting-legal rifle or shotgun.
Only handgun I've used is a 44 mag. on deer. It's a blast though. I'm not sure how a 10mm would do. The law wont allow it here (I don't think). It's been a while since I did it but I think they wanted a 30 cal up or a shotgun. in gun season. Then there's a bow season.
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