I can't imagine that you would need anything bigger than a .44 magnum for whitetails or feral hogs.
Personally, I believe most pistol hunting should probably be done at bowhunting distances. A scoped handgun can stretch that out a bit. Also, I would not want a ported handgun, unless I felt I had to have something that was approaching the .500, in the way it punished the shooter.
I would definitely go with Ruger, for hunting, because they are built to handle heavy handloads on a regular basis. Taurus is to be avoided, in my opinion, but S&W's are OK if you don't give them too steady of a diet of really heavy loads.
I don't hunt with handguns, but I do carry a 10mm Glock with me when the possibility of encountering feral hogs exists. It is a legitimate 25 yard handgun, with fixed iron sights, has power approaching that of a .41 Magnum, and has a 15+1 capacity. Not a classic hunting handgun, by any means, but I am capable of hitting the 'kill zone' on a hog at 25 yards with it, if I don't have a rifle, and that's why I wanted it. Feral hogs are considered vermin, where I hunt, and all hunters are expected to do their part to help thin them out.