Glocks have polygonal rifling, which doesn't work as well for most folks, when using lead bullets. The aftermarket barrels have conventional rifling and are recommended. Also, you will need a heavier recoil spring to shoot the hot, heavy loads.
Personally, I cannot see an advantage to having a 10mm that converts to .45 ACP. The 10mm is an excellent performer as a hunting round or self defense round, depending on how you set it up and what ammo you use. I love .45's, but can't imagine that I would downgrade from a 10mm to it, when the 10mm is such a fine chambering.