Well both are power punchers the G33 really is about 5%-10% smaller in all areas. if your talking about pocket carry that is a huge difference. IWB or OWB it wouldn't matter. Recoil with both will be about equal. I like the 357sig round and I no longer own a 45. When buying quality ammo the 357 sig ammo will cost about the same as quality 45 but cheap offbrand prctice ammo can be found in 45. During the ammo shortages in East TN 357 sig was plentyful more so than any other handgun caliber. It;s really up to you. Why are these the only two options? I think your limiting yourself. Remember 9mm in +P+ will give similar balistics to a standard 357 sig round.