Like most all modern autos, the G26 is safe to carry. No one would buy them if they weren't. Caution adivsed, as they will go off if you depress the trigger.
It can indeed serve as a CC/HD, since it is a firearm designed to be small enough to easily carry/conceal, and it does utilize a caliber that one could use to defend their home. You can also use high capacity magazines as well.
I wouldn't classify the Glock as the "most" reliable, as there are several other brands that are just as reliable (Sig, Walther, H&K). By the same token, there is nothing "more" reliable than a Glock. A G26 would make an excellent CC weapon.