A few thoughts.
1. I've never shot a Skyy, but I have shot several KelTecs (and own two). The KelTecs worked fine - both my P32 and P3AT are 100% reliable - so I'm not sure how much better Skyy could be.
2. Why .45GAP instead of, say, .40S&W? Does .45GAP have some special status - aside from being harder to find, more expensive, and reducing magazine capacity?
3. The Glock pistols chambering the GAP round have a 9mm frame with an ungainly, blocky slide the width of their .45ACP slides. Can Skyy overcome this and make the GAP slide the same width as the 9mm slide? It would seem like quite an engineering feat, especially in a subcompact pistol.
4. The GAP in a tiny pistol will recoil fairly strenuously, possibly enough to make split times unacceptably long. .40 has a similar problem, being right on the edge of realistic controllability in a pocket gun. I prefer 9mm in a small pistol.