I am about to buy a Target 22. Some of the decent ones seem to be the Beretta Neos, S&W 22A, Browning Buckmark and Ruger Mark III. Also, Sig makes the mosquito and Walther sells the P22.
I have looked at all of them and decided I wil buy a Ruger Mark III 22/45 (it has a traditional grip instead of the space gun grip of the plain Ruger Mark III's). The Sig and Walther are fun for plinking, but supposedly not as accurate as the target 22s. Most of the target 22s have all black sights. I don't like that. I want white dot sites. Ruger makes one model of the 22/45 w/ a 4" barrel and fixed white dot sights. The Rugers are a pain to disassemble compared to other brands. But, its what I've settled on. There is one at my local shop for $221. I hope to have it in a couple of months.