How small? Lessee...
My EDC is the AMT .45 Backup. It's just under six inches long, and four inches high. At its widest, it's an inch thick. I get six full-power .45 ACP shots, and then I reload with five more.
I'm getting old, and my arthritis bothers me, so I feel competent with it to only about 20 yards, but if I do my part I can make head shots at that distance.
It sits in my front pocket, in a Robert Mika holster, or it sits atop my bedside table within easy reach.
OK, so tell me: What am I sacrificing, carrying this tiny, powerful piece?
But for "serious social interaction," when we go to the dangerous little city on the nearby mainland to shop at Costco, I also carry either a custom-made, all-steel, Officer's-size 1911, or an aluminum-frame Star PD. Both are in .45 ACP, and both offer seven shots and a six-shot reload.
Both guns fit the same holster, and ride on the same belt, all by Bob Mernickle.
So what am I sacrificing when I use one of these?
Of course, if things get really serious, I have the option of either one—or both—of two full-size M1911A1s, both competition tuned but otherwise as-issued.
No sacrifice here.
Oh, and by-the-way, I sincerely hope that nobody on this forum is foolish enough to carry a pocket pistol "naked," and not in a pocket holster.
The pocket holster keeps excessive crud from building up inside the gun, keeps foreign objects from accidentally accessing the gun's trigger, and keeps the gun itself properly oriented in the pocket for easy access and quick presentation.
Furthermore, it is extremely unsafe, and also foolish, to carry anything else in the same pocket as the gun and its holster.