I can't vote in this poll because I don't know the experience and skill level of the person asking the question.
If the prospective owner is relatively inexperienced, I vote for the Glock for the reasons expressed by others: it's uncomplicated.
If the prospective owner has a good deal of experience and a good level of skill, I vote for the Commander-size 1911, but with an aluminum frame. Add an ambidextrous safety.
No matter what, I prefer a pistol in .45 ACP.