Me, I'd go with the Sig. Mainly because I like the feel more. I'm not a fan of DAO though and would rather have the P6/225 so I could have SA/DA and a hammer I can get hold of.

Between the two you have listed I'd still have to go with Sig for the feel an the fact I've had better reliability from Sig Sauer.

I've not used a 250, but if it's like the other Sigs I've used, I would get the Glock if I could only have one. I like the Glock's lower bore axis and shorter trigger reset, plus the fact that you can find more accessories for the Glock than just about any other pistol with the exception of the 1911.

I wouldn't sweat the decision too much, since you will probably end up with both of them sooner or later.....

I am not familiar with the Sig 250, but as far as I am concerned, Sig Sauer pistols are top notch. That being said, I can highly recommend the Glock 19. It is the only semi-auto pistol I own, and as long as I have a choice, it will be my first choice for pretty much any application I can think of.

If your choice is between a Sig or a Glock, I do not think you can go wrong. I for for sure the Glock will serve you very well.

I have the sig and the G-19. No question in my mind G-19

+1 for the Sig