I have in the distant past, yes. I carried a 4" S&W model 15 .38 Special concealed, occasionally, for several years with no problems. Get a good holster, and some thinner grips that won't snag and/or cause the cover garment to ride-up, and you'll be good-to-go. I used Hogue hard nylon pebble-grained finger-groove grips and a Bianchi Pistol Pocket thumb-break leather holster, but this all took place 30 years ago, so there may be better choices nowadays.
Originally Posted by gunner69
"Placement is power" -- seen in an article by Stephen A. Camp
(RIP, Mr. Camp; you will be remembered, and missed)