If I get another SA which I used to own a few of them BTW, 45 Colt was my most prized. Its presure spikes are far less than the famed 44 mag cartridge. Even in the .44 magnum cartridge I like my loadings much milder than wilder.
That is what is so nice about the .45 Colt cartridge it don't have to be wilder to be king on fhe range. I would trade my SRH .44 mag of a 45 Colt RH right now iffin the offer came up.
Just my .02 cents on the matter.